[Frontiers in Bioscience E6, 387-396, June 1, 2014] Antiepileptic drugs: Energy-consuming processes governing drug disposition
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چکیده
1. Abstract 2. Basic principle for corporal drug movement 2.1. Membrane transporters 2.2. Cardiac output distribution 2.3. Gastrointestinal-blood cycling 2.4. Drug distribution throughout the splanchnic organs 2.5. Efflux transportation, blood flow fraction, and drug recycling 3. Phenytoin 3.1. Michaelis-Menten consideration 3.2. Hepatic, intestinal, and renal contribution to phenytoin clearance 3.3. Carbamazepine interaction on phenytoin pharmacokinetics 4. Valproic acid 4.1. Non-linear pharmacokinetics of free valproate 4.2. Gastrointestinal-blood cycling of valproate 5. Conclusion 6. References
منابع مشابه
Antiepileptic drugs: Energy-consuming processes governing drug disposition.
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تاریخ انتشار 2014